天侑六年，志宗崩逝，其次女公主楚九龄（彭小苒 饰）质疑其叔父弑君篡位。履历家破人亡等一系列突如其来的变故，九龄下定决心查清泽州隐秘，揭露父皇被害实情，守护本人的至亲。九龄在成国公世子朱瓒（金瀚 饰）的援助下坚持济世救人，不竭地与奸佞的骚扰和抨击打击奋斗，建立了医馆九龄堂，治痘疮，护庶平易近。与此同时，朱瓒与清贵令郎宁云钊…

该剧是继《喷鼻蜜沉沉烬如霜》《冰糖炖雪梨》后“蜜糖三部曲”的收官之作。　　按照作家一度君华的同名小说改编，报告了人族皇室的一对孪生公主受阴谋算计，错嫁天界与沉渊界，在一次次哭笑不得的伪装中，原底细看两厌的错嫁夫妻们，竟逐步了解相知萌生爱意……

On her wedding day, Chu Jiu Ling (daughter of former crown prince) discovers that the person who killed her father is her uncle (the current Emperor). Just as she decides to seek revenge, she was almost killed by her husband, an imperial guard. Fortunately, she was saved by physician Zhang Qing Shan. Chu Jiu Ling retur…